Advanced Spinal Technologies, LLC.
Cunningham BW, Seiber B, Riggleman JR, Van Horn MR, Bhat A: An Investigational Study of a Dual‐layer, Chorion‐free Amnion Patch as a Protective Barrier Following Lumbar Laminectomy in a Sheep Model. J Tissue Eng. Regen Med. 2019;13(9):1664-71.
Wessell A, Flemming C, Caffes N, Johnsen P, Lewis E, Cunningham BW: and Sansur CA: Multi-directional flexibility testing of cortical versus pedicle screw stabilization in the osteoporotic lumbar spine: an in-vitro human cadaveric model. (Submission Date for World Neurosurgery6/2019).
Umekoji H, Cunningham BW, Murgatroyd AA, Sun X, Shirado O, McAfee, PC, Oda H: Spinal kinematics of dynamic posterior stabilization at the superior operative and adjacent levels in lumbar spinal reconstruction: an in vitro human cadaveric model. (Submission Date for The Journal of Neurosurgery – Spine 7/2019).
Cunningham, BW, Trontis AJ, Umekoji H, McAfee PC: A comprehensive biomechanical investigation of anterior lumbar interbody arthrodesis with intracorporeal screw fixation: an in vitro human dadaveric model. (Submission Date for The Journal of Neurosurgery – Spine 7/2019).
Trontis AJ, Cunningham, BW, Mullinix K, Sandhu F: Multidirectional flexibility and fixation properties of occipital bolt versus plate stabilization systems: emphasis on integrity of the osseous structures at the occipital implantation sites – (Submission Date for The Journal of Neurosurgery – Spine 7/2019)
Cunningham BW, Weiner DA, Kretzer RM, Tortolani PJ: Biomechanical properties of direct lateral interbody fusion with supplemental posterior instrumentation for adjacent level reconstruction: an in vitro human cadaveric model. (Submission Date for The Journal of Neurosurgery – Spine 8/2019).
Weiner DA, Cunningham BW, Sun X, McAfee, PC: Biomechanical and radiographic evaluation of an articulating interbody fusion device for TLIF; an in vitro human cadaveric model. (Submission Date for The Journal of Neurosurgery – Spine 10/2019).
The laboratory provides a basic scientific environment in which researchers, clinicians, and private industry corporations share the opportunity to pursue their orthopaedic and neurosurgical based research interests.
The laboratory facilities are divided into three primary areas: Biomechanics, Histology and Radiography.
Using systematic and scientific methodology, the primary focus of the laboratory is to investigate the biomechanical and biological response to spinal instrumentation, and determine the optimal materials and techniques to achieve stabilization and motion preservation in the spine while providing the utmost quality of life.
Basic Scientific Research
The laboratory collaborates with neurosurgeons and spine surgeons from The Johns Hopkins Hospital, University of Maryland, Union Memorial Hospital, and other prestigious national and international institutions to address basic scientific research issues related to reconstructive spinal surgery.
FDA Pre-Clinical Studies
The laboratory is a Good Laboratory Practices (GLP) compliant facility that performs extensive FDA pre-clinical studies using in-vitro cadaveric and in-vivo animal modeling to investigate new biomechanical and biological concepts in spinal reconstructive surgery. The majority of these studies are performed for private industry on a proprietary basis to support FDA 510K and IDE applications.